Hans-Leo
2007-10-09, 17:35
Measuring movement side effects using handwriting www.movalyzer.com
http://www.springerlink.com/content/y6817n7451762433/
Digital movement analysis, a new objective method of measuring tardive dyskinesia and drug-induced parkinsonian tremor: acceptability, reliability and validity
Flemming M. Nilsson1, Birgitte L. Hansen1, Christian Büchel2, Wagner F. Gattaz2 and Jes Gerlach1
(1) Department P, Han Hospital, DK-4000 Roskilde, Denmark
(2) Neurobiology Unit, Central Institute of Mental Health, D-68072 Mannheim, Germany
Received: 22 June 1995 Accepted: 28 August 1995
Abstract Digital movment analysis (DMA) is a new instrumental approach to assessing oral tardive dyskinesia (TD) by means of digital image processing of a video signal, tracking five paper dots placed around the patient's mouth. A total of 40 schizophrenic patients, 30 with and 10 without TD, were examined twice (with a 3-month interval) with this new device. The patients were further examined with two TD rating scales: the St. Hans Rating Scale for extrapyramidal syndromes (SHRS) and the Abnormal Involuntary Movement Scale (AIMS).
The schizophrenic patients accepted the instrumental assessment without any anxiety or resistance. The internal relibility of the apparatus was high, with correlation coefficients of 0.80–0.99. The DMA TD values correlated with the SHRS and AIMS scores with correlation coefficients of 0.48–0.73 indicating an acceptable, although not strong, concurrent validity. Fluctuations occurred from the first to the second examination independent of medication. For these fluctuations no correlation was found between DMA values and rating scores. Finally, the DMA device was able to detect perioral tremor as a sign of parkinsonism.
It has been concluded that DMA is a useful supplement to classical TD rating, although further validity evaluation is warranted.
Key words Tardive dyskinesia - Movement disorder - Parkinsonism - Instrumental assessment - Digital image processing
http://www.springerlink.com/content/y6817n7451762433/
Digital movement analysis, a new objective method of measuring tardive dyskinesia and drug-induced parkinsonian tremor: acceptability, reliability and validity
Flemming M. Nilsson1, Birgitte L. Hansen1, Christian Büchel2, Wagner F. Gattaz2 and Jes Gerlach1
(1) Department P, Han Hospital, DK-4000 Roskilde, Denmark
(2) Neurobiology Unit, Central Institute of Mental Health, D-68072 Mannheim, Germany
Received: 22 June 1995 Accepted: 28 August 1995
Abstract Digital movment analysis (DMA) is a new instrumental approach to assessing oral tardive dyskinesia (TD) by means of digital image processing of a video signal, tracking five paper dots placed around the patient's mouth. A total of 40 schizophrenic patients, 30 with and 10 without TD, were examined twice (with a 3-month interval) with this new device. The patients were further examined with two TD rating scales: the St. Hans Rating Scale for extrapyramidal syndromes (SHRS) and the Abnormal Involuntary Movement Scale (AIMS).
The schizophrenic patients accepted the instrumental assessment without any anxiety or resistance. The internal relibility of the apparatus was high, with correlation coefficients of 0.80–0.99. The DMA TD values correlated with the SHRS and AIMS scores with correlation coefficients of 0.48–0.73 indicating an acceptable, although not strong, concurrent validity. Fluctuations occurred from the first to the second examination independent of medication. For these fluctuations no correlation was found between DMA values and rating scores. Finally, the DMA device was able to detect perioral tremor as a sign of parkinsonism.
It has been concluded that DMA is a useful supplement to classical TD rating, although further validity evaluation is warranted.
Key words Tardive dyskinesia - Movement disorder - Parkinsonism - Instrumental assessment - Digital image processing