Caligiuri, M.P., Teulings, H.L., Dean, C.E., Niculescu, A.B., Lohr, J.B. (2010).
Handwriting Movement Kinematics for Quantifying EPS in Patients Treated with Atypical Antipsychotics.
Psychiatry Research, 177, 77-83.
Becky Farley, Sara Derosa, Gail Koshland, & Arend Van Gemmert (2010).Results from 59 psychosis patients (age 51+-9) and 46 healthy comparison subjects (age 42+-9) from the University of California San Diego, Minneapolis Veterans Administration Medical Center, and Indiana University School of Medicine in Indianapolis revealed (1) slowing and dysfluency in patients compared to controls, (2) differences across medications, and (3) across daily dose. These findings support the ecological validity of movement analysis as an objective behavioral biomarker for quantifying the effects of antipsychotic medication and dose on the motor system. NIH National Institute of Mental Health R44 MH073192
The LSVT® BIG and LOUD training protocol transfers to an untrained handwriting task in early Parkinson disease
NASPSPA, Tucson, AZ, USA, June 10-12 2010.
Mohammed L, Found B , Caligiuri MP & Rogers D (2009).
Pen pressure as a discriminatory feature between genuine and forged signatures.
In Vinter, A., & Velay, J-L. (Eds). Proceedings of the 14th Biennial Conference of the International Graphonomics Society (IGS2009), 13-16 September 2009, Dijon, France. Dijon: Vidonne Press. ISBN 9-782746-604841. pp 26-29.
Caligiuri MP, Teulings HL, Dean CE, Niculescu AB, Lohr J. (2009).The authenticity of a signature was examined at the San Diego Sheriff’s Crime Laboratory, CA, USA and Document Examination Unit, jointly with Victoria Police Forensic Services Department, and the Handwriting Analysis & Research Laboratory, School of Human Biosciences, La Trobe University, Victoria, Australia and the Department of Psychiatry, University of California, San Diego, CA, USA. Common examinations are based on static signatures limiting the estimation of dynamic information. Pen pressure variation is an integral part of each person’s handwriting behavior. Pen pressure differences between genuine and forged signatures were examined in 33 writers (mean age 39, singatures were text-based (n= 17), mixed (n=9), or stylized (n=4)). The genuine signatures have higher pen pressure than the forgeries. There was greater variability in the pen pressure of the forged signatures in comparison to the genuine signatures supporting that pen pressure can be used as a discriming factor for the authenticity of signatures independently of the forger's own signature style.
Handwriting movement analyses for monitoring drug-induced motor side effects in schizophrenia patients treated with risperidone.
Hum Mov Sci. 2009 Oct;28(5):633-42. Epub 2009 Aug 18.
FREE ACCESS: This manuscript NIHMS139909 has been loaded into PubMed Central for public access: http://www.pubmedcentral.gov/article...?artid=274907574 participants were tested at the University of California San Diego, Minneapolis Veterans Administration Medical Center, and Indiana University School of Medicine in Indianapolis. 21 risperidone-treated schizophrenia or schizoaffective disorder (SZ), 6 unmedicated schizophrenia patients (age 45+-11), and 47 normal healthy volunteers participated in this study (age 42+110). Risperidone-treated participants exhibited lower movement velocities during simple loops than unmedicated patients. Movement dysfluency during sentence writing increased with dose. In contrast, we found no association between observer-based rating of Extrapyramidal Symptoms (EPS) and daily dose. These findings support the importance of movement-based measures to monitor EPS in medicated schizophrenia patients. NIH Grant R44 MH073192
Saltuklaroglu T, Teulings HL, Robbins M. (2009).
Differential levels of speech and manual dysfluency in adults who stutter during simultaneous drawing and speaking tasks.
Hum Mov Sci. 2009 Oct;28(5):643-54. Epub 2008 Nov 4.
Hughes B, Van Gemmert A & Stelmach G (2009).15 adults who stutter (ages 18–51, mean 28) from the University of Tennessee, Speech and Hearing Clinic and a control group of 15 (ages 21–50, mean 32) participated. Frequency of stuttering events in the speaking tasks and measured pen stroke duration and pen stroke dysfluency (normalized jerk) were estimated. Episodes of stuttering showed more dysfluencies with pen movements. Stuttering was virtually eliminated in choral reading (reduced by 97%), but manual dysfluency was reduced by only 47% relative to reading aloud. Episodes of stuttering and motor dysfluency seem related to neural interconnectivity between manual and speech processes. Professional development grant from the University of Tennessee.
The intermittency of Braille reading finger velocities.
In Vinter, A., & Velay, J-L. (Eds). Proceedings of the 14th Biennial Conference of the International Graphonomics Society (IGS2009), 13-16 September 2009, Dijon, France. Dijon: Vidonne Press. ISBN 9-782746-604841. pp 190-193.
Gilles Clément, Corinna Lathan, Anna Lockerd, and Angie Bukley (2009).16 blind persons (age 43+-15) at Arizona State University and the University of Auckland, New Zealand scanned a Braille text with their fingers. Movements were recorded by a tablet and a pen attached to a finger. The pen movements revealed linguistic Braille-reading effects.
Mental representation of spatial cues in microgravity: Writing and drawing tests
Acta Astronautica, 64 (7), p.678-681, Apr 2009.
Harralson, HH, Teulings HL & Farley B (2009).9 subjects (age 24–49) were tested both on the ground and on board the CNES Airbus A300 Zero-G airplane performing 30 parabolic flight paths producing episodes of 22 s of microgravity. Motor tests complemented by psychophysics measurements were done by the Centre National de la Recherche Scientifique, UMR 5549 CNRS-UPS Cerveau et Cognition, Toulouse, France, Russ College of Engineering and Technology, Ohio University, Athens, OH, USA, AnthroTronix Inc., Silver Spring, MD, USA. The results indicate that the vertical height of handwritten characters and drawings is reduced in microgravity compared to normal gravity, suggesting that the mental representation of the height of objects and the environment change during short-term microgravity. NASA/ESA
Handwriting variability in movement disorder patients and effects of fatigue.
In Vinter, A., & Velay, J-L. (Eds). Proceedings of the 14th Biennial Conference of the International Graphonomics Society (IGS2009), 13-16 September 2009, Dijon, France. Dijon: Vidonne Press. ISBN 9-782746-604841. pp 103-107.
9 Parkinson's disease (PD) patients (Hoehn & Yahr Stages 1 and 2) and 1 Essential Tremor (ET) patient (mean age 66) and 7 healthy controls (mean age 56) of the University of Arizona, Department of Physiology, Tucson, AZ, USA produced their signature and wrote “George Washington” in cursive (prefatigued condition). Three trials of each task were performed on a pen tablet with inking pen. Participants then wrote a sentence in their normal handwriting, cursive loops, a more complex cursive pattern, and an Archimedes spiral. Then they wrote again "George Washington" and their signature (fatigued condition). The fatigue analysis compares first and last signatures and writing of "George Washington". The visual image analysis showed differences due to fatigue. In the dynamic analysis from the pen tablet recording, the patients were slower and more variable than the controls. Fatigue increases variability in motor-disordered handwriting more severely than in healthy handwriting.